Used as antioxidant, preservative, and vitamin supplement
EINECS No
200-066-2
Properties
White to slightly yellowish crystalline powder, odorless, readily soluble in water, sensitive to light and air
Grade
Pharmaceutical/IP/USP/BP/Food Grade
Density
1.65 Gram per cubic centimeter(g/cm3)
Physical Form
Powder
Appearance
White to Slightly Yellow Crystalline Powder
Solubility
Freely soluble in water, slightly soluble in alcohol
Taste
Sour
Structural Formula
See C6H8O6; structural diagram available on request
Storage
Store in cool, dry place away from light
Shape
Crystalline/Granular
Usage
Pharmaceuticals, food and beverage, cosmetics, animal feed
Product Type
Vitamins
Purity
99% minimum
CAS No
50-81-7
HS Code
29362700
Ph Level
2.1 (5% solution)
Specific Optical Rotation
+20.5 to +21.5 (in water)
Heavy Metals
<10 ppm
Packaging Type
25 kg fiber drum / HDPE drum / customized packing
Loss on Drying
Max 0.4%
Stability
Stable under recommended storage conditions
Particle Size
Standard/Custom available
Allergen Information
Allergen free (as per manufacturing process)
Moisture Content
Max 0.10%
Ascorbic acid Trade Information
Minimum Order Quantity
1 Kilograms
Delivery Time
1 Week
About Ascorbic acid
Ascorbic acid (Vitamin C) acts as both an Active Pharmaceutical Ingredient (API) and a versatile excipient, primarily as an antioxidant to stabilize formulations, but also as a component in developing nanoparticles, for drug solubilization, and as a pH adjuster, requiring specific excipients like microcrystalline cellulose, starch, mannitol, and lubricants (e.g., magnesium stearate, stearic acid) to overcome its poor compressibility and moisture sensitivity in solid dosage forms like tablets. Its derivatives (e.g., ascorbyl glycoside, ascorbyl palmitate) are used in specialized drug delivery systems.
Sweeteners/Flavoring: Mannitol (for taste masking in chewables/mouth-dissolving tablets).
Key Roles in Formulations
Antioxidant: Protects APIs and the formulation from oxidative degradation, extending shelf life, crucial in radiopharmaceuticals.
Solubilizer: Ascorbic acid derivatives (like ascorbyl glycoside) can help solubilize poorly soluble drugs and form nanoparticles, improving dissolution.
Stabilizer: Prevents color changes and potency loss in liquid formulations and supplements.
Formulation Challenges & Solutions
Poor Compressibility: Ascorbic acid doesn't compact well; requires effective lubricants and specialized excipients like modified fats, MCC, and Aerosil (silica) for strong, fast-disintegrating tablets.
Moisture Sensitivity: Needs protection from moisture, stored tightly closed, with careful excipient selection to maintain stability.
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