Ethanol (Ethyl Alcohol) is a multi-functional excipient used across diverse dosage forms. It primarily serves as a solvent, co-solvent, and antimicrobial preservative.
Functional Roles as an Excipient
Solubility Enhancer: As a co-solvent, it significantly increases the solubility of poorly water-soluble Active Pharmaceutical Ingredients (APIs), facilitating their incorporation into oral liquids, syrups, and injectables.
Antimicrobial Preservative: In concentrations above 1520%, ethanol inhibits bacterial and fungal growth, extending the shelf-life of liquid and topical preparations.
Extraction Solvent: Used to extract active constituents from botanical sources for herbal medicines and mother tinctures.
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