Sodium Starch Glycolate (SSG) powder is a vital pharmaceutical excipient, acting as a superdisintegrant that rapidly swells and breaks down tablets/capsules in water, releasing medicine faster for better absorption; it's a white, fine, free-flowing powder from starch, also used as a binder, gelling, or suspending agent in solid dosage forms, ensuring drug efficacy.
Key Characteristics:
Appearance: Fine, white to off-white, odorless powder.
Origin: Derived from starch (potato, corn, rice) and modified.
Function: Primary role as a superdisintegrant in tablets and capsules.
Mechanism: Rapidly absorbs water, swells significantly, creating pressure to disintegrate the dosage form.
Uses in Pharmaceuticals:
Disintegration: Breaks down tablets/capsules quickly for faster drug release.
Binding: Can act as a binder to hold tablet ingredients together.